Psychological Characteristics of Children and Adolescents Who Have Undergone COVID-19: Possibilities of Correction.

The article is about topical issues of the psychological features of the long-term consequences of post-COVID syndrome in children and adolescents. We have described the most frequent residual manifestations of SARS-CoV-2 infection alongside with an analysis of the characteristics of the emotional and behavioral health of children and adolescents. The authors of article have analyzed modern approaches and recommendations for changing the lifestyle, psychological support of patients with the elimination of stress factors and body stress resistance increase. Also in article are presented main symptoms and signs associated with emotional and behavioral responses to stress in children and adolescents. The necessity of early detection and psychological correction of the symptoms of post-COVID syndrome and its inherent stress manifestations is substantiated as well as the stress resistance increase using physiological approaches of micronutrient correction with bioorganic magnesium substances.Copyright © 2022, Professionalnye Izdaniya. All rights reserved.

Factors of Stress Resistance in Doctors and Medical Workers during the COVID-19 Pandemic

Purpose. The purpose of this study was to analyze the severity of stress reactions and highlight stress resistance factors in medical workers under the COVID-19 pandemic. Materials and methods. The methodological complex included: social and demographic questionnaire;the Perceived Stress Scale-10 questionnaire;State-Trait Anxiety Inventory;Maslach Burnout Inventory, Russian adaptation, version for healthcare workers);Russian-language version of the 24-itemHEXACO six-factor Personality Inventory;Russian-language version of Kuhl and Fuhrmann Self-regulation Study Methodology (Selbststeuerungs-Inventar – SSI). A total of 318 medical workers (mean age 38.7±11.6 years) participated in the online survey in the period between Apr. 27, 2020, and Nov. 20, 2021. Results. The results of the study revealed that a low level of stress resistance and a high level of emotional burnout were mostly detected in medical workers with specialized secondary education under the age of 30, in female medical staff and among respondents who did not have their own children. The dynamics of changes in burnout rates directly corresponded to the dynamics of changes in morbidity rates during the pandemic periods. Psychological factors of medical staff stress resistance under the COVID-19 pandemic conditions were identified, including such personality traits as extraversion, openness to new experiences and conscientiousness, a developed capacity for self-regulation, will development, orientation to act after failures, as well as congruence of own feelings and readiness to integrate contradictions. Conclusion. The conclusion summarizes the results and presents the limitations and prospects of this study. © 2023, Professionalnye Izdaniya. All rights reserved.

Psychological Resources for Coping with Fear of COVID-19 and Negative Psychological Emotional States among Students of Russia and Kazakhstan

The article presents the analysis results of stress resistance and basic beliefs as psychological resources for coping with fear of COVID-19 and negative psychological and emotional states on the sample of Russian (N=2310) and Kazakh (N=500) students (71.2% — women, average age 19.7). A higher level of stress resistance and basic belief expression in Benevolence of the World Around and Perceiving the World as Meaningful and Social Justice among Kazakh students in comparison with Russian ones is revealed, which is determined by the peculiarities formed in the conditions of the nomadic lifestyle of the Kazakh culture, based on the principles of mutual support and mutual assistance, trust and openness. It is shown that, regardless of the country and gender, high level of stress resistance and expression of basic beliefs are accompanied by lower indicators of fear of COVID-19 and the absence of negative psychological and emotional states associated with it, which suggests the universality of these psychological resources as a buffer that mitigates the traumatic effect of the pandemic situation © 2022, Cultural-Historical Psychology.All Rights Reserved.

Risk Factors and Mechanisms of Cardiovascular Diseases in Posttraumatic Stress Disorder Model in Wistar Rats as Dependent on Stress Resistance and Age.

The article focuses on the pathogenetic mechanisms of posttraumatic stress disorder (PTSD), which is associated with psychological stress because of the coronavirus pandemic. The molecular mechanisms responsible for disease susceptibility in some individuals and stress resistance in others are amongst crucial research interests of experimental and clinical medicine. Priority data were obtained to indicate that distortions of synthesis and metabolism and, most significantly, a switch between two energy transport forms, glucose and lipids, underlie myocardial dysfunction in young and old stress-sensitive Wistar rats in a PTSD model. Histochemistry and polarization microscopy showed energy deficit in cardiomyocytes and signs of ischemic and hypoxic areas emerging in the myocardium as a result of an accumulation of NADH and NADPH, which initiate excessive production of reactive oxygen species.

Microbial silver resistance mechanisms: recent developments.

In this mini-review, after a brief introduction into the widespread antimicrobial use of silver ions and nanoparticles against bacteria, fungi and viruses, the toxicity of silver compounds and the molecular mechanisms of microbial silver resistance are discussed, including recent studies on bacteria and fungi. The similarities and differences between silver ions and silver nanoparticles as antimicrobial agents are also mentioned. Regarding bacterial ionic silver resistance, the roles of the sil operon, silver cation efflux proteins, and copper-silver efflux systems are explained. The importance of bacterially produced exopolysaccharides as a physiological (biofilm) defense mechanism against silver nanoparticles is also emphasized. Regarding fungal silver resistance, the roles of metallothioneins, copper-transporting P-type ATPases and cell wall are discussed. Recent evolutionary engineering (adaptive laboratory evolution) studies are also discussed which revealed that silver resistance can evolve rapidly in bacteria and fungi. The cross-resistance observed between silver resistance and resistance to other heavy metals and antibiotics in bacteria and fungi is also explained as a clinically and environmentally important issue. The use of silver against bacterial and fungal biofilm formation is also discussed. Finally, the antiviral effects of silver and the use of silver nanoparticles against SARS-CoV-2 and other viruses are mentioned. To conclude, silver compounds are becoming increasingly important as antimicrobial agents, and their widespread use necessitates detailed understanding of microbial silver response and resistance mechanisms, as well as the ecological effects of silver compounds. Figure created with BioRender.com.

Psychological Characteristics of Children and Adolescents Who Have Undergone COVID-19: Possibilities of Correction

The article is about topical issues of the psychological features of the long-term consequences of post-COVID syndrome in children and adolescents. We have described the most frequent residual manifestations of SARS-CoV-2 infection alongside with an analysis of the characteristics of the emotional and behavioral health of children and adolescents. The authors of article have analyzed modern approaches and recommendations for changing the lifestyle, psychological support of patients with the elimination of stress factors and body stress resistance increase. Also in article are presented main symptoms and signs associated with emotional and behavioral responses to stress in children and adolescents. The necessity of early detection and psychological correction of the symptoms of post-COVID syndrome and its inherent stress manifestations is substantiated as well as the stress resistance increase using physiological approaches of micronutrient correction with bioorganic magnesium substances. © 2022, Professionalnye Izdaniya. All rights reserved.